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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
26.67
Human Site:
T52
Identified Species:
45.13
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
T52
N
L
M
S
Q
L
G
T
K
Q
D
S
S
K
L
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
T52
N
L
M
S
Q
L
G
T
K
Q
D
S
S
K
L
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
T52
N
L
M
S
Q
L
G
T
K
Q
D
S
S
K
L
Dog
Lupus familis
XP_535342
274
31382
T52
N
L
M
S
Q
L
G
T
K
Q
D
S
S
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
T52
N
L
M
S
Q
L
G
T
K
Q
D
S
S
K
L
Rat
Rattus norvegicus
O70257
261
29832
L52
T
P
E
L
R
Q
Q
L
Q
Q
E
Q
Q
Y
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
A45
L
Q
Q
L
Q
H
S
A
N
Q
L
A
K
E
T
Chicken
Gallus gallus
XP_001232002
272
30779
Q52
M
S
Q
L
G
T
K
Q
D
S
S
K
L
Q
E
Frog
Xenopus laevis
NP_001079671
259
29246
K54
L
R
N
H
L
Q
E
K
I
Q
Y
T
H
K
I
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
T52
Q
L
G
T
R
P
D
T
P
E
L
Q
D
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
S66
K
K
H
S
A
I
L
S
A
P
Q
T
D
E
K
Honey Bee
Apis mellifera
XP_396269
271
30684
D52
N
Q
L
G
S
S
T
D
S
Q
E
L
R
N
Q
Nematode Worm
Caenorhab. elegans
O16000
291
33234
S65
K
K
H
S
A
I
L
S
N
P
V
N
D
Q
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
T59
R
L
V
N
S
I
G
T
P
K
D
T
L
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
13.3
0
13.3
20
N.A.
6.6
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
26.6
6.6
26.6
46.6
N.A.
33.3
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
0
0
8
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
8
0
43
0
22
0
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
8
15
0
0
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
43
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
8
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
22
0
0
8
0
0
0
0
0
8
% I
% Lys:
15
15
0
0
0
0
8
8
36
8
0
8
8
43
15
% K
% Leu:
15
50
8
22
8
36
15
8
0
0
15
8
15
0
50
% L
% Met:
8
0
36
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
43
0
8
8
0
0
0
0
15
0
0
8
0
8
0
% N
% Pro:
0
8
0
0
0
8
0
0
15
15
0
0
0
0
0
% P
% Gln:
8
15
15
0
43
15
8
8
8
65
8
15
8
15
8
% Q
% Arg:
8
8
0
0
15
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
8
0
50
15
8
8
15
8
8
8
36
36
0
0
% S
% Thr:
8
0
0
8
0
8
8
50
0
0
0
22
0
0
15
% T
% Val:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _